Status quo as far as I've heard. I just want them to alleviate the worst side effects prior to FDA approval. After all, I don't think anyone wants effects like hair loss, worse skin effects the PN, cardiac, GI, or neurological. It is difficult to be patient. Please keep trying ot'her options so that may be you won't need Nemo. Also, I hope they are investigating manufacturing strategy to keep the cost affordable!

As for alternatives to these questionable medications: 1. I bought a shingles book called "The Shingles Solution" by Julissa Clay, and started following the natural guidelines for healing which involved mostly changing my diet (lots of veges and fruit, avoid almonds and nuts, follow the list of high in arginine and low in licine food, take a lisine supplement, bathe and soak often in Epson salts (or dead sea salt), bentonite clay and a few drops of rosemary oil or lavendar oil, doubled my magnesium intake and Vit D and omegas, quit alcohol, avoid chocolate to heal shingles, avoid coffee (that was the hard one, but i switched to Ryze mushroom coffee). I feel these changes have decreased my itching and while they cleared up my shingles, they also are healing my PN and dermatitis. It's not perfect but it's much improved, so I'm sticking to the dietary changes for a while longer to see what happens. I'm left to believe from this experience that the shingles diet might be worth trying for PN! Book also recommended liver detoxing - I was detoxing my kidneys but wasn't paying attention to my liver.
2. I still like the MMS protocol by Jim Humble ( can order his book from his website, don't think you'll find it on Amazon or at Barnes and Noble because it flies in the face of all western conventional treatments). His protocol heals dozens of "mysterious" diseases, and I think you might agree with me that PN is a "mystery disease". Well, good luck.

Hey Tina! It sure would!

Thank you for the update Cathy. Sometimes the side effects are worse than the problem. Like my breathing issue after 10 months on dupixent, I have both asthma and COPD, and it's like my pipe just closed, nothing in, nothing out. After the 2nd time that happened, I talked to my Dermo and stopped taking it. I now wish I was on it as I'm itching like heck, but, Adbry doesn't seam to be helping much.
I still have fingers crossed for Nemo, it would be great to have something that actually works that was created for PN.

Looks like Galderma has priority review from the FDA as of February, 2024. The company is running a clinical trial which looks like it is ongoing for 184 weeks.(approximately 3 plus years). The FDA wants proof of effectiveness.