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Should I Have My PN Diagnosis Confirmed By Biopsy?

A MyPrurigoTeam Member asked a question 💭
New York, NY

My dermatologist didn't do one. My nodules are painless and they blanch when I press on them...is that what PN nodules do? My original diagnosis last winter was spongiosis/atopic dermatitis. I've moved from MyEczemaTeam to this group now. Should I return to derm for a biopsy?

September 28, 2024
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A MyPrurigoTeam Member

A biopsy can help the professionals determine what's going on. With PN, it can have different sides to it, excema, atopic dermatitis, and still be PN looming there. My understanding is that a biopsy needs to be done when in a flare with an active nodule/lesion. Some Drs can verify it without biopsy, it just depends.
Usually a PN nodule goes thru stages, whether it itches or not, whether it runs into a lesion or not.
The group you are on is what is helpful for you. We are here for information sharing and support. We do not diagnose, that is your Drs to do that.
You can look through information under the Resources tab and see if that helps you find more out.

September 28, 2024
A MyPrurigoTeam Member

It's important to have an accurate diagnosis for prurigo nodularis (PN). Here are some key points from my knowledge base that might help:

- Biopsy for Diagnosis: A skin biopsy is often used to diagnose PN. It involves removing a piece of skin to examine under a microscope for specific changes, such as excess keratin and Show Full Answer

It's important to have an accurate diagnosis for prurigo nodularis (PN). Here are some key points from my knowledge base that might help:

- Biopsy for Diagnosis: A skin biopsy is often used to diagnose PN. It involves removing a piece of skin to examine under a microscope for specific changes, such as excess keratin and inflammatory cells.
- Symptoms and Nodules: PN nodules are typically itchy, thickened, and may have a distinct pattern. They can be symmetrical and located on common sites like the arms, legs, back, and abdomen.
- Differential Diagnosis: Since PN symptoms can overlap with other conditions like atopic dermatitis, a biopsy can help confirm the diagnosis and ensure appropriate treatment.

Given your history and current symptoms, it might be beneficial to return to your dermatologist for a biopsy to confirm the diagnosis and rule out other conditions.

September 28, 2024
A MyPrurigoTeam Member

Thank you.

September 28, 2024

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