It sounds like you're looking for alternative treatments for prurigo nodularis. Here are some options mentioned in the knowledge base:

1. Neuromodulating Agents
- Gabapentin or Pregabalin: These can help reduce itch by preventing nerve cells from becoming activated. However, they can cause drowsiness and increase the Show Full Answer

It sounds like you're looking for alternative treatments for prurigo nodularis. Here are some options mentioned in the knowledge base:

1. Neuromodulating Agents:
- Gabapentin or Pregabalin: These can help reduce itch by preventing nerve cells from becoming activated. However, they can cause drowsiness and increase the risk of falls.

2. Thalidomide:
- Used for difficult cases but requires frequent monitoring due to its toxicity and potential side effects like sensory issues and embolism.

3. Cannabidiol (CBD):
- May help reduce itch, inflammation, and pain. Available in creams, lotions, and gels.

4. Capsaicin Cream:
- Proven to reduce skin inflammation and itch. A small study showed significant improvement in pruritus and skin lesions.

5. Monoclonal Antibodies:
- Nemolizumab: Blocks part of the immune system and may help with itching.

6. Opioid Receptor Antagonists:
- Naloxone and Naltrexone: May help block immune system or nervous system processes.

Always consult with your dermatologist to find the best treatment plan for you.

 This AI-generated response comes from MyPrurigoTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

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