You might want to try Nemluvio. It is specificly for PN, and I am seeing considerable improvement after 1 and a half months.

It has helped with my intense itching! When it’s almost time to get another shot I start the itching again which means no sleep or rest! It’s a terrible thing to have

This was a miracle for
Me but I missed few months and now it’s not working so well
Switching to new drug nemluvio

Hope you find what works for you… been on dupixent for a year and a half and so far … it’s working … no real side effects besides the weight gain where I inject myself so started doing it on my butt… my legs are big as it is (get it from my momma… lol) but so far so good …

The side effects get to many of us. So it is finding a system of treatment that works for us, well, one that we can safely live with. I hope you find your path.