After almost 20 of riding this PN train I have come to some opinions. I have tried many suggestions and approaches. PN is not a result of diet or environment. It is a protein some how switched on that normally would not be. PN is similar to mycelium, ( imo ) the nodules are connected to each other deep within the skin layers. It seems this protein creates the itch and we scratch and this in turn creates the swelling , hard core and top. The cycle is one of itch, scratch, bleed, relief. Then the burning /pain cycle begins. My most resent attempt at control was very helpful. Organic oregano, 1 drop under tongue x 2 a day, it greatly subdued the inflammation. I also take about 20,000 Vit D3 at night. I did this for several months with a good deal of relief. Most recently I have been approved for Dupixent. I had my first 2 shots this past week. So far not much has happened and I was told it’s about 3 months before noticeable improvement. I have found it to be a user friendly medication, no side effects. I will continue with oregano and D 3 as well. I will post any changes as I will have my injections every 2 weeks.
We never know what someone may be dealing with so be kind to yourself and to others.

Hello
I have been on the duprixent since December no change , the only side effect I have had is my thyroid it’s not happy now . The doctor put me on a vitamin called NAC 600mg two times a day . He said it’s old school I will let you know if it works . I am going to try your metas well .

So encouraging to feel your proactive status. Best wishes for you finding more relief

Do they itch on one side at a time too? Like left arm today, right arm tomorrow?

Great question I have the same thing 🤔